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A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease
A major contributor to treatment failure in Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is that current treatment regimens do not address the drug-insensitivity of transiently dormant T. cruzi amastigotes. Here, we demonstrated that use of a currently available...
Shranjeno v:
izdano v: | Sci Transl Med |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2020
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7926267/ https://ncbi.nlm.nih.gov/pubmed/33115952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abb7656 |
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