The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington’s Disease Mice

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an early and central disease mechanism which is accompanied by epigenetic alterations in HD. Previous st...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Hecklau, Katharina, Mueller, Susanne, Koch, Stefan Paul, Mehkary, Mustafa Hussain, Kilic, Busra, Harms, Christoph, Boehm-Sturm, Philipp, Yildirim, Ferah
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925995/
https://ncbi.nlm.nih.gov/pubmed/33679321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.616886
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