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APOE and Alzheimer’s Disease: From Lipid Transport to Physiopathology and Therapeutics
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations. One risk factor for developing AD is the APOE gene coding for the apolipoprotein E protein (apoE). Humans have three versions of APOE gene: ε...
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| Publicado no: | Front Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925634/ https://ncbi.nlm.nih.gov/pubmed/33679311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.630502 |
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