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Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology

Cancer is generally characterized by acquired genomic aberrations in a broad spectrum of types and sizes, ranging from single nucleotide variants to structural variants (SVs). At least 30% of cancers have a known pathogenic SV used in diagnosis or treatment stratification. However, research into the...

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書目詳細資料
發表在:NPJ Precis Oncol
Main Authors: van Belzen, Ianthe A. E. M., Schönhuth, Alexander, Kemmeren, Patrick, Hehir-Kwa, Jayne Y.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925608/
https://ncbi.nlm.nih.gov/pubmed/33654267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00155-6
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