Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder

Macular Telangiectasia Type 2 (MacTel) is a rare degenerative retinal disease with complex genetic architecture. We performed a genome-wide association study on 1,067 MacTel patients and 3,799 controls, which identified eight novel genome-wide significant loci (p < 5 × 10(−8)), and confirmed all...

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Publié dans:Commun Biol
Auteurs principaux: Bonelli, Roberto, Jackson, Victoria E., Prasad, Aravind, Munro, Jacob E., Farashi, Samaneh, Heeren, Tjebo F. C., Pontikos, Nikolas, Scheppke, Lea, Friedlander, Martin, Egan, Catherine A., Allikmets, Rando, Ansell, Brendan R. E., Bahlo, Melanie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925591/
https://ncbi.nlm.nih.gov/pubmed/33654266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01788-w
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