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Thymic origins of autoimmunity—lessons from inborn errors of immunity

During their intrathymic development, nascent T cells are empowered to protect against pathogens and to be operative for a life-long acceptance of self. While autoreactive effector T (Teff) cell progenitors are eliminated by clonal deletion, the intrathymic mechanisms by which thymic regulatory T ce...

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Detalhes bibliográficos
Publicado no:Semin Immunopathol
Main Authors: Bacchetta, Rosa, Weinberg, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925499/
https://ncbi.nlm.nih.gov/pubmed/33532929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-020-00835-8
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