Signaling pathways in human osteoclasts differentiation: ERK1/2 as a key player

Little is known about the signaling pathways involved in the differentiation of human osteoclasts. The present study evaluated the roles of the Ras/PI3K/Akt/mTOR, Ras/Raf/MEK1/2/ERK1/2, calcium-PKC, and p38 signaling pathways in human osteoclast differentiation. Mononuclear cells were isolated from...

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Bibliographic Details
Published in:Mol Biol Rep
Main Authors: Pennanen, Paula, Kallionpää, Roope A., Peltonen, Sirkku, Nissinen, Liisa, Kähäri, Veli-Matti, Heervä, Eetu, Peltonen, Juha
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925492/
https://ncbi.nlm.nih.gov/pubmed/33486672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-020-06128-5
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