Astragaloside IV inhibits palmitic acid-induced apoptosis through regulation of calcium homeostasis in mice podocytes

Loss of podocytes is a hallmark of diabetic nephropathy, and a growing body of evidence indicates that podocytes are susceptible to palmitic acid (PA). We have previously shown that AS-IV inhibited PA-induced podocyte apoptosis by activating sarcoendoplasmic reticulum Ca(2+) ATPase (SERCA), which in...

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Detalhes bibliográficos
Publicado no:Mol Biol Rep
Main Authors: Zang, Yingjun, Liu, Shuang, Cao, Aili, Shan, Xiangyu, Deng, Wenjuan, Li, Zhijun, Wang, Hao, Wang, Yunman, Wang, Li, Peng, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925475/
https://ncbi.nlm.nih.gov/pubmed/33606151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-021-06204-4
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