Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication

Dengue virus (DENV) is a mosquito-borne virus that infects upward of 300 million people annually and has the potential to cause fatal hemorrhagic fever and shock. While the parameters contributing to dengue immunopathogenesis remain unclear, the collapse of redox homeostasis and the damage induced b...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ferrari, Matteo, Zevini, Alessandra, Palermo, Enrico, Muscolini, Michela, Alexandridi, Magdalini, Etna, Marilena P., Coccia, Eliana M., Fernandez-Sesma, Ana, Coyne, Carolyn, Zhang, Donna D., Marques, Ernesto T. A., Olagnier, David, Hiscott, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925186/
https://ncbi.nlm.nih.gov/pubmed/32999020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01551-20
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