Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication

Dengue virus (DENV) is a mosquito-borne virus that infects upward of 300 million people annually and has the potential to cause fatal hemorrhagic fever and shock. While the parameters contributing to dengue immunopathogenesis remain unclear, the collapse of redox homeostasis and the damage induced b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Ferrari, Matteo, Zevini, Alessandra, Palermo, Enrico, Muscolini, Michela, Alexandridi, Magdalini, Etna, Marilena P., Coccia, Eliana M., Fernandez-Sesma, Ana, Coyne, Carolyn, Zhang, Donna D., Marques, Ernesto T. A., Olagnier, David, Hiscott, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Virus-Cell Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925186/
https://ncbi.nlm.nih.gov/pubmed/32999020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01551-20
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