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Structure-Based Deep Mining Reveals First-Time Annotations for 46 Percent of the Dark Annotation Space of the 9,671-Member Superproteome of the Nucleocytoplasmic Large DNA Viruses

We conducted an exhaustive search for three-dimensional structural homologs to the proteins of 20 key phylogenetically distinct nucleocytoplasmic DNA viruses (NCLDV). Structural matches covered 429 known protein domain superfamilies, with the most highly represented being ankyrin repeat, P-loop NTPa...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Mirzakhanyan, Yeva, Gershon, Paul David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925184/
https://ncbi.nlm.nih.gov/pubmed/32999026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00854-20
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