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Aneuploidy in human eggs: contributions of the meiotic spindle

Human eggs frequently contain an incorrect number of chromosomes, a condition termed aneuploidy. Aneuploidy affects ∼10–25% of eggs in women in their early 30s, and more than 50% of eggs from women over 40. Most aneuploid eggs cannot develop to term upon fertilization, making aneuploidy in eggs a le...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Thomas, Christopher, Cavazza, Tommaso, Schuh, Melina
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925012/
https://ncbi.nlm.nih.gov/pubmed/33449109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200043
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