Influence of the heme distal pocket on nitrite binding orientation and reactivity in Sperm Whale myoglobin

Nitrite binding to recombinant wild-type Sperm Whale myoglobin (SWMb) was studied using a combination of spectroscopic methods including room-temperature magnetic circular dichroism. These revealed that the reactive species is free nitrous acid and the product of the reaction contains a nitrite ion...

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Bibliographic Details
Published in:Biochem J
Main Authors: Tse, Wilford, Whitmore, Nathan, Cheesman, Myles R., Watmough, Nicholas J.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2021
Subjects:
Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925009/
https://ncbi.nlm.nih.gov/pubmed/33543749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200596
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