Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice

Adjuvant tamoxifen therapy improves survival in breast cancer patients. Unfortunately, long-term treatment comes with side effects that impact health and quality of life, including hot flashes, changes in bone density, and fatigue. Partly due to a lack of proven animal models, the tissues and cells...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Zhang, Zhi, Park, Jae Whan, Ahn, In Sook, Diamante, Graciel, Sivakumar, Nilla, Arneson, Douglas, Yang, Xia, van Veen, J Edward, Correa, Stephanie M
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924955/
https://ncbi.nlm.nih.gov/pubmed/33647234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63333
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