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tRNA sequences can assemble into a replicator

Can replication and translation emerge in a single mechanism via self-assembly? The key molecule, transfer RNA (tRNA), is one of the most ancient molecules and contains the genetic code. Our experiments show how a pool of oligonucleotides, adapted with minor mutations from tRNA, spontaneously formed...

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Foilsithe in:eLife
Main Authors: Kühnlein, Alexandra, Lanzmich, Simon A, Braun, Dieter
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924937/
https://ncbi.nlm.nih.gov/pubmed/33648631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63431
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