An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19

We aim to establish a comprehensive COVID-19 autoantigen atlas in order to understand autoimmune diseases caused by SARS-CoV-2 infection. Based on the unique affinity between dermatan sulfate and autoantigens, we identified 348 proteins from human lung A549 cells, of which 198 are known targets of a...

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Veröffentlicht in:bioRxiv
Hauptverfasser: Wang, Julia Y., Zhang, Wei, Roehrl, Michael W., Roehrl, Victor B., Roehrl, Michael H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924268/
https://ncbi.nlm.nih.gov/pubmed/33655248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.21.432171
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