Pharmacodynamic Drug–Drug Interaction on Human Peripheral Blood Mononuclear Cells Between Everolimus and Tacrolimus at the Therapeutic Concentration Range in Renal Transplantation

BACKGROUND: Everolimus (EVL) plus tacrolimus (TAC) therapy is effective and safe in renal transplantation. However, the pharmacokinetic and pharmacodynamic information for EVL combined with TAC is limited. We investigated the pharmacodynamic drug–drug interaction between EVL and TAC at their therape...

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Detalhes bibliográficos
Publicado no:Ann Transplant
Main Authors: Okihara, Masaaki, Takeuchi, Hironori, Akiyama, Shinichi, Yoshinaga, Reichi, Osato, Sayuri, Akashi, Isao, Kihara, Yu, Konno, Osamu, Iwamoto, Hitoshi, Oda, Takashi, Tanaka, Sachiko, Unezaki, Sakae, Hirano, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2021
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924008/
https://ncbi.nlm.nih.gov/pubmed/33633104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.928817
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