Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation

Epithelial cells of the female reproductive tract (FRT) participate in the initial innate immunity against viral infections. Poly(dA:dT) is a synthetic analog of B form double-stranded (ds) DNA which can activate the interferon (IFN) signaling pathway-mediated antiviral immunity through DNA-dependen...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Shao, Dan-Dan, Meng, Feng-Zhen, Liu, Yu, Xu, Xi-Qiu, Wang, Xu, Hu, Wen-Hui, Hou, Wei, Ho, Wen-Zhe
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923882/
https://ncbi.nlm.nih.gov/pubmed/33664729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.598884
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