The Srs2 helicase dampens DNA damage checkpoint by recycling RPA from chromatin

The DNA damage checkpoint induces many cellular changes to cope with genotoxic stress. However, persistent checkpoint signaling can be detrimental to growth partly due to blockage of cell cycle resumption. Checkpoint dampening is essential to counter such harmful effects, but its mechanisms remain t...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Dhingra, Nalini, Kuppa, Sahiti, Wei, Lei, Pokhrel, Nilisha, Baburyan, Silva, Meng, Xiangzhou, Antony, Edwin, Zhao, Xiaolan
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2021
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923681/
https://ncbi.nlm.nih.gov/pubmed/33602817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020185118
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