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The Srs2 helicase dampens DNA damage checkpoint by recycling RPA from chromatin
The DNA damage checkpoint induces many cellular changes to cope with genotoxic stress. However, persistent checkpoint signaling can be detrimental to growth partly due to blockage of cell cycle resumption. Checkpoint dampening is essential to counter such harmful effects, but its mechanisms remain t...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923681/ https://ncbi.nlm.nih.gov/pubmed/33602817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020185118 |
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