Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants

BACKGROUND: Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advances in next generation sequencing. This limitation constrai...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Riaz, Nasir, Leung, Preston, Barton, Kirston, Smith, Martin A., Carswell, Shaun, Bull, Rowena, Lloyd, Andrew R., Rodrigo, Chaturaka
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923462/
https://ncbi.nlm.nih.gov/pubmed/33653280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07460-1
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