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Frataxins Emerge as New Players of the Intracellular Antioxidant Machinery

Frataxin is a mitochondrial protein which deficiency causes Friedreich’s ataxia, a cardio-neurodegenerative disease. The lack of frataxin induces the dysregulation of mitochondrial iron homeostasis and oxidative stress, which finally causes the neuronal death. The mechanism through which frataxin re...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Uceda, Ana Belén, Donoso, Josefa, Frau, Juan, Vilanova, Bartolomé, Adrover, Miquel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923443/
https://ncbi.nlm.nih.gov/pubmed/33672495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020315
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