Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness

Pruritus is a common symptom of inflammatory skin conditions, including atopic dermatitis (AD). Although primary sensory neurons that transmit pruritic signals are well-cataloged, little is known about the neuronal alterations that occur as a result of skin disruption in AD. To address this question...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Braz, Joao M., Dembo, Todd, Charruyer, Alexandra, Ghadially, Ruby, Fassett, Marlys S., Basbaum, Allan I.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923356/
https://ncbi.nlm.nih.gov/pubmed/33602818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021386118
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