IL-4Rα blockade reduces influenza-associated morbidity in a murine model of allergic asthma

BACKGROUND: Asthma was identified as the most common comorbidity in hospitalized patients during the 2009 H1N1 influenza pandemic. We determined using a murine model of allergic asthma whether these mice experienced increased morbidity from pandemic H1N1 (pH1N1) viral infection and whether blockade...

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Bibliografske podrobnosti
izdano v:Respir Res
Main Authors: Shahangian, Kimia, Ngan, David A., Chen, H. H. Rachel, Oh, Yeni, Tam, Anthony, Wen, Jing, Cheung, Chung, Knight, Darryl A., Dorscheid, Delbert R., Hackett, Tillie L., Hughes, Michael R., McNagny, Kelly M., Hirota, Jeremy A., Niikura, Masahiro, Man, S. F. Paul, Sin, Don D.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922715/
https://ncbi.nlm.nih.gov/pubmed/33653328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01669-0
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