BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice

Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor endoglin. Endoglin haploinsufficiency results in vascular malformations and impaired neoangiogenesis. Furthermore, HHT1 patients display an impaired immune response. To d...

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Publicado en:Int J Mol Sci
Main Authors: Bakker, Wineke, Dingenouts, Calinda K. E., Lodder, Kirsten, Wiesmeijer, Karien C., de Jong, Alwin, Kurakula, Kondababu, Mager, Hans-Jurgen J., Smits, Anke M., de Vries, Margreet R., Quax, Paul H. A., Goumans, Marie José T. H.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922601/
https://ncbi.nlm.nih.gov/pubmed/33670533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042010
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