5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism

Autism spectrum disorder (ASD) covers a range of neurodevelopmental disorders involving impairments in communication and repetitive and stereotyped patterns of behavior and reciprocal social interaction. 5-Aminoisoquinolinone (5-AIQ), a PARP-1 inhibitor, has neuroprotective and anti-inflammatory eff...

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Detalhes bibliográficos
Publicado no:Brain Sci
Main Authors: Alhosaini, Khaled, Ansari, Mushtaq A., Nadeem, Ahmed, Bakheet, Saleh A., Attia, Sabry M., Alhazzani, Khalid, Albekairi, Thamer H., Al-Mazroua, Haneen A., Mahmood, Hafiz M., Ahmad, Sheikh F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922312/
https://ncbi.nlm.nih.gov/pubmed/33671196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci11020249
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