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Therapeutic Efficacy and Biodistribution of Paclitaxel-Bound Amphiphilic Cyclodextrin Nanoparticles: Analyses in 3D Tumor Culture and Tumor-Bearing Animals In Vivo

The uniqueness of paclitaxel’s antimitotic action mechanism has fueled research toward its application in more effective and safer cancer treatments. However, the low water solubility, recrystallization, and side effects hinder the clinical success of classic paclitaxel chemotherapy. The aim of this...

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Publicat a:Nanomaterials (Basel)
Autors principals: Varan, Gamze, Varan, Cem, Öztürk, Süleyman Can, Benito, Juan M., Esendağlı, Güneş, Bilensoy, Erem
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922126/
https://ncbi.nlm.nih.gov/pubmed/33670527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano11020515
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