Increased Regulatory T Cells and Decreased Myeloid-Derived Suppressor Cells Induced by High CCL17 Levels May Account for Normal Incidence of Cancers among Patients with Atopic Dermatitis

The incidence of cancers in atopic dermatitis (AD) is not increased, although the Th2-dominant environment is known to downregulate tumor immunity. To gain mechanistic insights regarding tumor immunity in AD, we utilized CCL17 transgenic (TG) mice overexpressing CCL17, which is a key chemokine in AD...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Morimura, Sohshi, Sugaya, Makoto, Oka, Tomonori, Suga, Hiraku, Miyagaki, Tomomitsu, Tsunemi, Yuichiro, Asano, Yoshihide, Sato, Shinichi
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2021
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922104/
https://ncbi.nlm.nih.gov/pubmed/33670758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042025
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