Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

Microglia are ubiquitous central nervous system (CNS)-resident macrophages that maintain homeostasis of neural tissues and protect them from pathogen attacks. Yet, their differentiation in different compartments remains elusive. We performed single-cell RNA-seq to compare microglial subtypes in the...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Zheng, Junying, Ru, Wenjuan, Adolacion, Jay R., Spurgat, Michael S., Liu, Xin, Yuan, Subo, Liang, Rommel X., Dong, Jianli, Potter, Andrew S., Potter, S Steven, Chen, Ken, Chen, Rui, Varadarajan, Navin, Tang, Shao-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921843/
https://ncbi.nlm.nih.gov/pubmed/33718838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102186
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