Cysteine metabolic circuitries: druggable targets in cancer

To enable survival in adverse conditions, cancer cells undergo global metabolic adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling on three different levels: first, in its free form, in redox control, as a component of the antioxidant glutathione or its involve...

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Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Bonifácio, Vasco D. B., Pereira, Sofia A., Serpa, Jacinta, Vicente, João B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921671/
https://ncbi.nlm.nih.gov/pubmed/33223534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01156-1
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