L-Carnitine protects against tacrolimus-induced renal injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling

Reducing immunosuppressant-related complications using conventional drugs is an efficient therapeutic strategy. L-carnitine (LC) has been shown to protect against various types of renal injury. In this study, we investigated the renoprotective effects of LC in a rat model of chronic tacrolimus (TAC)...

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Gepubliceerd in:Acta Pharmacol Sin
Hoofdauteurs: Zheng, Hai-lan, Zhang, Hai-yue, Zhu, Chun-lian, Li, Hui-ying, Cui, Sheng, Jin, Jian, Piao, Shang-guo, Jiang, Yu-ji, Xuan, Mei-ying, Jin, Ji-zhe, Jin, Ying-shun, Lee, Jung-pyo, Chung, Byung-ha, Choi, Bum-soon, Yang, Chul-woo, Li, Can
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Singapore 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921136/
https://ncbi.nlm.nih.gov/pubmed/32555441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0449-8
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