Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1

Hypertrophic scar (HS) formation is a skin fibroproliferative disease that occurs following a cutaneous injury, leading to functional and cosmetic impairment. To date, few therapeutic treatments exhibit satisfactory outcomes. The mechanical force has been shown to be a key regulator of HS formation,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: He, Jiahao, Fang, Bin, Shan, Shengzhou, Xie, Yun, Wang, Chuandong, Zhang, Yifan, Zhang, Xiaoling, Li, Qingfeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921104/
https://ncbi.nlm.nih.gov/pubmed/33649312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03481-6
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