CBL0137 increases the targeting efficacy of Rovalpituzumab tesirine against tumour-initiating cells in small cell lung cancer

Small cell lung cancer (SCLC) is characterised by high relapse rates. Tumour-initiating cells (TICs) are responsible for drug resistance and recurrence of cancer. Rovalpituzumab tesirine (Rova-T), a potent humanised antibody–drug conjugate, selectively targets delta-like protein 3, which is highly e...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Lindner, Daniel J., Wildey, Gary, Parker, Yvonne, Dowlati, Afshin, Stark, George R., De, Sarmishtha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921085/
https://ncbi.nlm.nih.gov/pubmed/33257843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01192-x
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