Pharmacogenomic Profile and Adverse Drug Reactions in a Prospective Therapeutic Cohort of Chagas Disease Patients Treated with Benznidazole

Chagas disease remains a major social and public health problem in Latin America. Benznidazole (BZN) is the main drug with activity against Trypanosoma cruzi. Due to the high number of adverse drug reactions (ADRs), BZN is underprescribed. The goal of this study was to evaluate the genetic and trans...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Franco, Lucas A. M., Moreira, Carlos H. V., Buss, Lewis F., Oliveira, Lea C., Martins, Roberta C. R., Manuli, Erika R., Lindoso, José A. L., Busch, Michael P., Pereira, Alexandre C., Sabino, Ester C.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920452/
https://ncbi.nlm.nih.gov/pubmed/33669428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041960
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