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Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway

OBJECTIVES: TTP488, an antagonist of the receptor for advanced glycation end-products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer’s disease (AD). However, the mechanism underlying the protective action of TTP488 against AD has not yet been fully explored. MET...

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Pubblicato in:Clinics (Sao Paulo)
Autori principali: Yang, Lijuan, Liu, Yepei, Wang, Yuanyuan, Li, Junsheng, Liu, Na
Natura: Artigo
Lingua:Inglês
Pubblicazione: Faculdade de Medicina / USP 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920406/
https://ncbi.nlm.nih.gov/pubmed/33681944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2021/e2348
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