Baseline serum angiopoietin-2 and VEGF levels predict the deterioration of the liver functional reserve during lenvatinib treatment for hepatocellular carcinoma

A deteriorated liver functional reserve during systemic therapy for unresectable hepatocellular carcinoma (HCC) causes poor patient outcomes. We aimed to identify predictive factors associated with the deterioration of Child-Pugh score at 8 weeks after lenvatinib initiation. Patients with adequate c...

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Udgivet i:PLoS One
Main Authors: Shigesawa, Taku, Suda, Goki, Kimura, Megumi, Maehara, Osamu, Tokuchi, Yoshimasa, Kubo, Akinori, Yamada, Ren, Furuya, Ken, Baba, Masaru, Kitagataya, Takashi, Suzuki, Kazuharu, Ohara, Masatsugu, Kawagishi, Naoki, Nakai, Masato, Sho, Takuya, Natsuizaka, Mitsuteru, Morikawa, Kenichi, Ogawa, Koji, Sakamoto, Naoya
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920365/
https://ncbi.nlm.nih.gov/pubmed/33647018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247728
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