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DNA Methylation, Mechanisms of FMR1 Inactivation and Therapeutic Perspectives for Fragile X Syndrome

Among the inherited causes of intellectual disability and autism, Fragile X syndrome (FXS) is the most frequent form, for which there is currently no cure. In most FXS patients, the FMR1 gene is epigenetically inactivated following the expansion over 200 triplets of a CGG repeat (FM: full mutation)....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomolecules
Egile Nagusiak: Nobile, Veronica, Pucci, Cecilia, Chiurazzi, Pietro, Neri, Giovanni, Tabolacci, Elisabetta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920310/
https://ncbi.nlm.nih.gov/pubmed/33669384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020296
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