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Synthesis and Characterization of Chitosan-Based Nanodelivery Systems to Enhance the Anticancer Effect of Sorafenib Drug in Hepatocellular Carcinoma and Colorectal Adenocarcinoma Cells

The formation of two nanodelivery systems, Sorafenib (SF)-loaded chitosan (SF-CS) and their folate-coated (SF-CS-FA) nanoparticles (NPs), were developed to enhance SF drug delivery on human Hepatocellular Carcinoma (HepG2) and Colorectal Adenocarcinoma (HT29) cell lines. The ionic gelation method wa...

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Vydáno v:Nanomaterials (Basel)
Hlavní autoři: Ruman, Umme, Buskaran, Kalaivani, Pastorin, Giorgia, Masarudin, Mas Jaffri, Fakurazi, Sharida, Hussein, Mohd Zobir
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920308/
https://ncbi.nlm.nih.gov/pubmed/33669332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano11020497
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