Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer

SIMPLE SUMMARY: Insulin-like growth factor II (IGF-II) is a potent growth factor implicated in several cancer types. The IGF-II gene shares its locus with the long non-coding RNA, H19. IGF-II/H19 is an imprinted gene—a phenomenon where only the maternal copy is expressed. The silencing of the patern...

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Publicado en:Cancers (Basel)
Autores principales: Kingshott, Georgina, Biernacka, Kalina, Sewell, Alex, Gwiti, Paida, Barker, Rachel, Zielinska, Hanna, Gilkes, Amanda, McCarthy, Kathryn, Martin, Richard M., Lane, J. Athene, McGeagh, Lucy, Koupparis, Anthony, Rowe, Edward, Oxley, Jon, Holly, Jeff M. P., Perks, Claire M.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920081/
https://ncbi.nlm.nih.gov/pubmed/33669311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040825
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