Examining the Relationship between Circulating CD4− CD8− Double-Negative T Cells and Outcomes of Immuno-Checkpoint Inhibitor Therapy—Looking for Biomarkers and Therapeutic Targets in Metastatic Melanoma

Background: The role of circulating CD4−/CD8− double-negative T cells (DNTs) in the immune response to melanoma is poorly understood, as are the effects of checkpoint inhibitors on T cell subpopulations. Methods: We performed a basal and longitudinal assessment of circulating immune cells, including...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Strippoli, Sabino, Fanizzi, Annarita, Negri, Antonio, Quaresmini, Davide, Nardone, Annalisa, Armenio, Andrea, Sciacovelli, Angela Monica, Massafra, Raffaella, De Risi, Ivana, De Tullio, Giacoma, Albano, Anna, Guida, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920027/
https://ncbi.nlm.nih.gov/pubmed/33669266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020406
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