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Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data

Like most solid tumors, glioblastoma multiforme (GBM) harbors multiple overexpressed and mutated genes that affect several signaling pathways. Suppressing tumor growth of solid tumors like GBM without toxicity may be achieved by small molecules that selectively modulate a collection of targets acros...

詳細記述

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書誌詳細
出版年:ACS Chem Biol
主要な著者: Xu, David, Zhou, Donghui, Bum-Erdene, Khuchtumur, Bailey, Barbara J., Sishtla, Kamakshi, Liu, Sheng, Wan, Jun, Aryal, Uma K., Lee, Jonathan A., Wells, Clark D., Fishel, Melissa L., Corson, Timothy W., Pollok, Karen E., Meroueh, Samy O.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919753/
https://ncbi.nlm.nih.gov/pubmed/32243127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00078
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