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Meta-analysis of chromosomal aberrations as a biomarker of exposure in healthcare workers occupationally exposed to antineoplastic drugs

Many antineoplastic drugs used to treat cancer, particularly alkylating agents and topoisomerase inhibitors, are known to induce genetic damage in patients. Elevated levels of chromosomal aberrations, micronuclei, and DNA damage have been documented in cancer patients. Elevations in these same bioma...

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Detalhes bibliográficos
Publicado no:Mutat Res
Main Authors: Roussel, Christine, Witt, Kristine L., Shaw, Peter B., Connor, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919743/
https://ncbi.nlm.nih.gov/pubmed/31416576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2017.08.002
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