The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects

Serotonin communication operates mainly in the extracellular space and cerebrospinal fluid (CSF), using volume transmission with serotonin moving from source to target cells (neurons and astroglia) via energy gradients, leading to the diffusion and convection (flow) of serotonin. One emerging concep...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Borroto-Escuela, Dasiel O., Ambrogini, Patrizia, Chruścicka, Barbara, Lindskog, Maria, Crespo-Ramirez, Minerva, Hernández-Mondragón, Juan C., Perez de la Mora, Miguel, Schellekens, Harriët, Fuxe, Kjell
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919680/
https://ncbi.nlm.nih.gov/pubmed/33672070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041927
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