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Modulation of IGF2 Expression in the Murine Thymus and Thymic Epithelial Cells Following Coxsackievirus-B4 Infection

Coxsackievirus B4 (CV-B4) can infect human and murine thymic epithelial cells (TECs). In a murine TEC cell line, CV-B4 can downregulate the transcription of the insulin-like growth factor 2 (Igf2) gene coding for the self-peptide of the insulin family. In this study, we show that CV-B4 infections of...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Michaux, Hélène, Halouani, Aymen, Trussart, Charlotte, Renard, Chantal, Jaïdane, Hela, Martens, Henri, Geenen, Vincent, Hober, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919294/
https://ncbi.nlm.nih.gov/pubmed/33672010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9020402
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