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Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes

Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to characterise accurately using conventional sequencing methods. Here, we show how the use of a third-generation (long-read) sequencing and informatic approach can overcome thi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kinkar, Liina, Gasser, Robin B., Webster, Bonnie L., Rollinson, David, Littlewood, D. Timothy J., Chang, Bill C.H., Stroehlein, Andreas J., Korhonen, Pasi K., Young, Neil D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918261/
https://ncbi.nlm.nih.gov/pubmed/33670420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041811
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