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A SNaPshot Assay for Determination of the Mannose-Binding Lectin Gene Variants and an Algorithm for Calculation of Haplogenotype Combinations

Mannose-binding lectin (MBL) deficiency caused by the variability in the MBL2 gene is responsible for the susceptibility to and severity of various infectious and autoimmune diseases. A combination of six single nucleotide polymorphisms (SNPs) has a major impact on MBL levels in circulation. The aim...

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Bibliographic Details
Published in:Diagnostics (Basel)
Main Authors: Mrazkova, Jana, Sistek, Petr, Lochman, Jan, Izakovicova Holla, Lydie, Danek, Zdenek, Borilova Linhartova, Petra
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918147/
https://ncbi.nlm.nih.gov/pubmed/33668563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11020301
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