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Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy

The peripheral effects of ω-conotoxins, selective blockers of N-type voltage-gated calcium channels (Ca(V)2.2), have not been characterised across different clinically relevant pain models. This study examines the effects of locally administered ω-conotoxin MVIIA, GVIA, and CVIF on mechanical and th...

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Publicado en:Mar Drugs
Autores principales: Hasan, Md. Mahadhi, Starobova, Hana, Mueller, Alexander, Vetter, Irina, Lewis, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917901/
https://ncbi.nlm.nih.gov/pubmed/33670311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19020106
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