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CRISPR Deletion of a SVA Retrotransposon Demonstrates Function as a cis-Regulatory Element at the TRPV1/TRPV3 Intergenic Region

SINE-VNTR-Alu (SVA) retrotransposons are a subclass of transposable elements (TEs) that exist only in primate genomes. TE insertions can be co-opted as cis-regulatory elements (CREs); however, the regulatory potential of SVAs has predominantly been demonstrated using bioinformatic approaches and rep...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Price, Emma, Gianfrancesco, Olympia, Harrison, Patrick T., Frank, Bernhard, Bubb, Vivien J., Quinn, John P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917899/
https://ncbi.nlm.nih.gov/pubmed/33671852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041911
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