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GLP-1 alleviates NLRP3 inflammasome-dependent inflammation in perivascular adipose tissue by inhibiting the NF-κB signalling pathway

OBJECTIVES: To study the effect of glucagon-like peptide 1 (GLP-1) on NLR family pyrin domain containing 3 (NLRP3) inflammasome-induced inflammation in perivascular adipose tissue (PVAT) of Zucker diabetic fatty (ZDF) rats and the underlying role of nuclear factor (NF)-κB signalling. METHODS: Thirty...

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Bibliografiske detaljer
Udgivet i:J Int Med Res
Main Authors: Chen, Xiangheng, Huang, Qiuling, Feng, Juling, Xiao, Zhongsheng, Zhang, Xiaoling, Zhao, Lei
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917887/
https://ncbi.nlm.nih.gov/pubmed/33641439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060521992981
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