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Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic Efficacy against Painful Diabetic Neuropathy

Impaired rate-dependent depression (RDD) of the spinal H-reflex occurs in diabetic rodents and a sub-set of patients with painful diabetic neuropathy. RDD is unaffected in animal models of painful neuropathy associated with peripheral pain mechanisms and diabetic patients with painless neuropathy, s...

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Publicado en:Diagnostics (Basel)
Autores principales: Lee-Kubli, Corinne A., Zhou, XiaJun, Jolivalt, Corinne G., Calcutt, Nigel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917809/
https://ncbi.nlm.nih.gov/pubmed/33670344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11020283
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