Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System

BACKGROUND: Hyperosmosis stress (HS) was a key pathological factor in the development of dry eye disease (DED). Nicotinamide mononucleotide (NMN) demonstrated protective effects in the corneal damage, however, its role in the HS-induced DED remained unclear. METHODS: A NaCl based HS in-vitro model (...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Meng, Yi-Fang, Pu, Qi, Dai, San-You, Ma, Qian, Li, Xinyu, Zhu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917392/
https://ncbi.nlm.nih.gov/pubmed/33658825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S292764
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