Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis

INTRODUCTION: It is a clinically well-established fact that patients with diabetes have very poor stroke outcomes. Yet, the underlying mechanisms remain largely unknown. Our previous studies showed that male diabetic animals show greater hemorrhagic transformation (HT), profound loss of cerebral vas...

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Publicat a:Transl Stroke Res
Autors principals: Abdul, Yasir, Li, Weiguo, Ward, Rebecca, Abdelsaid, Mohammed, Hafez, Sherif, Dong, Guangkuo, Jamil, Sarah, Wolf, Victoria, Johnson, Maribeth H., Fagan, Susan C., Ergul, Adviye
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917163/
https://ncbi.nlm.nih.gov/pubmed/32875455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-020-00844-7
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